The statement Not true of Selective Cox - 2 inhibitor is________________?
Correct answer: C. Safe in patients with renal insufficiency
- A. The analgesic and anti-inflammatory effects identical to that of Non-selective NSAID
- B. They do not offer the cardio protective effect
- C. Safe in patients with renal insufficiency
- D. Fewer incidence of gastrointestinal side effect
Explanation
Selective COX-2 inhibitors can still impair renal prostaglandin-dependent blood flow, so they are not safe in renal insufficiency. They cause fewer gastrointestinal effects but do not provide aspirin-like cardioprotection and may increase cardiovascular risk.
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