The single most important laboratory test for determining the virulence of staphylococci is___________?

Correct answer: C. Detection of coagulase

  • A. Mannitol fermentation
  • B. Hemolysis of sheep erythrocytes
  • C. Detection of coagulase
  • D. The catalase test

Explanation

Coagulase converts fibrinogen to fibrin and helps Staphylococcus aureus form a protective clot, making coagulase the key laboratory marker associated with staphylococcal virulence. Catalase distinguishes staphylococci from streptococci but does not specifically indicate virulence.

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