The phenomenon of transcription in HIV life cycle occurs in:
Correct answer: A. Nucleus
- A. Nucleus
- B. Cytoplasm
- C. Inside viral capsid
- D. None of these
Explanation
Option A is correct.In HIV infected helper T-cells, the process of transcription occurs in nucleus while the process of reverse transcription occurs in cytoplasm.The HIV virus undergoes a number of processes in the nucleus, cytoplasm, and viral capsid during its replication cycle.In the nucleus:Reverse transcription: The viral RNA is reverse transcribed into DNA by the reverse transcriptase enzyme.Integration: The DNA is integrated into the DNA of the host cell by the integrase enzyme.Transcription: The integrated DNA is transcribed into RNA by the host cell's DNA polymerase.In the cytoplasm:Translation: The RNA is translated into proteins by the host cell's ribosomes.Protease cleavage: The proteins are cleaved by the protease enzyme into their active forms.Assembly: The viral proteins and RNA assemble into new virions.In the viral capsid:Maturation: The virions are matured by the removal of the proteins that are not needed for infection.Budding: The virions bud from the host cell membrane and are released into the extracellular environment.
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