The nucleophilic addition reactions of group are catalyzed by bases or acids. An acid catalyzed reaction:
Correct answer: B. Increases electrophilic character of carbon of carbonyl group
- A. Increases nucleophilic character of attacking reagent
- B. Increases electrophilic character of carbon of carbonyl group
- C. Increases both electrophilic and nucleophilic character
- D. Has no effect on the reactivity of carbonyl groups
Explanation
Option B is correct.The nucleophilic addition reactions of carbonyl groups are catalyzed by bases or acids. Base-catalyzed nucleophilic addition reactions In a base-catalyzed nucleophilic addition reaction, the base abstracts a proton from the carbonyl group, creating a negatively charged carbonyl carbon. This makes the carbonyl carbon more electrophilic, and it is more likely to be attacked by a nucleophile. The following reaction is an example of a base-catalyzed nucleophilic addition reaction: RCHO + H2O → R-C(OH)2 Here, RCHO is the starting compound, H2O is the nucleophile, and H+ is the leaving group. Acid-catalyzed nucleophilic addition reactions In an acid-catalyzed nucleophilic addition reaction, the acid protonates the carbonyl oxygen, creating a positively charged carbonyl oxygen. This makes the carbonyl carbon less electron-rich, and it is less likely to be attacked by a nucleophile. However, the positively charged carbonyl oxygen is also a good leaving group, and it can be easily displaced by a nucleophile. The following reaction is an example of an acid-catalyzed nucleophilic addition reaction: RCHO + NH3 → R-CH=NH Here, RCHO is the starting compound, NH3 is the nucleophile, and H+ is the leaving group.
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Aldehydes and ketones contain the polar carbonyl group, but aldehydes are generally more readily oxidised and more reactive than ketones. Coverage includes preparation by oxidation or reduction routes, nucleophilic addition of reagents such as hydrogen cyanide and bisulfite, and tests that distinguish aldehydes from ketones.
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