Moderate

The neurotransmitter released at the neuromuscular junction of skeletal muscle is

Correct answer: C. acetylcholine

  • A. noradrenaline
  • B. dopamine
  • C. acetylcholine
  • D. GABA

Explanation

Acetylcholine diffuses across the synaptic cleft and depolarises the sarcolemma, and the resulting action potential spreads down the T tubules to release calcium. The enzyme cholinesterase then destroys it quickly, so each nerve impulse produces one twitch rather than continuous contraction. Nerve gases and some insecticides are lethal because they block that enzyme.

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About Muscle Contraction

Muscle contraction is explained by the sliding filament model, in which myosin heads pull actin filaments within sarcomeres using ATP. The topic covers calcium, troponin, tropomyosin, the neuromuscular junction and relaxation, with attention to how filament length stays almost constant while the sarcomere shortens.

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