Moderate

The most common enzyme deficiency in man is___________?

Correct answer: A. Glucose 6 phosphate dehydrogenase

  • A. Glucose 6 phosphate dehydrogenase
  • B. Glucose 6 phosphatase
  • C. Hexokinase
  • D. Glucose 1,6 diphosphatase

Explanation

Glucose-6-phosphate dehydrogenase deficiency is the most common clinically significant inherited enzyme deficiency worldwide. Its red-cell deficiency can cause oxidant-triggered haemolysis because NADPH and reduced glutathione are not maintained adequately.

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