The first clinical application of gene therapy over a 4 year old girl was for_________?
Correct answer: A. Adenosine deaminase deficiency
- A. Adenosine deaminase deficiency
- B. Adenosine deficiency
- C. Growth deficiency
- D. Adenine deficiency
Explanation
The first widely recognised clinical gene-therapy trial treated severe combined immunodeficiency caused by adenosine deaminase deficiency by introducing a functional ADA gene into the patient's cells. Adenosine deficiency is the likely distractor because it sounds similar, but the disorder specifically involves the ADA enzyme.
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Biotechnology applies genetic engineering, cell culture and recombinant DNA methods to medicine and public health. The material includes production of insulin, vaccines and antibiotics, diagnostic techniques, gene therapy, genetically modified organisms and the ethical concerns surrounding manipulation of human genes.
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