Moderate

The enzyme phosphofructo kinase-1 is strongly activated by_______________?

Correct answer: D. Fructose 2,6 bis phosphate

  • A. Cyclic AMP
  • B. Adenosine tri phosphate
  • C. Citrate
  • D. Fructose 2,6 bis phosphate

Explanation

Fructose 2,6-bisphosphate is the strongest activator of phosphofructokinase-1 and promotes glycolysis. ATP and citrate inhibit this enzyme, while cyclic AMP acts mainly through regulation of fructose 2,6-bisphosphate levels.

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