The complementary base pairing in DNA is important because it:

Correct answer: D. Allows DNA act as a genetic blueprint during replication

  • A. Maintains the tertiary structure of enzymes
  • B. Provides energy for all cell metabolism
  • C. Enables protein to fold properly
  • D. Allows DNA act as a genetic blueprint during replication

Explanation

Because adenine always pairs with thymine and guanine with cytosine, each strand specifies the sequence of the other, so separating the two gives two templates that produce identical copies. This is precisely what Watson and Crick noted on proposing the structure. Protein folding and enzyme structure depend on interactions between amino acid side chains, not on base pairing.

This question appeared on the UHS MDCAT 2025 paper, which you can sit online with every answer explained.

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About Structure of DNA

DNA structure includes nucleotides made of deoxyribose, phosphate and nitrogenous bases, arranged in two antiparallel polynucleotide strands. Questions cover the double helix, phosphodiester and hydrogen bonds, complementary base pairing between adenine and thymine and between guanine and cytosine, and the significance of major and minor grooves.

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