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The CO-Hb bond is:

Correct answer: A. More stable than the O2-Hb bond

  • A. More stable than the O2-Hb bond
  • B. Less stable than the O2-Hb bond
  • C. The stability of both bonds is approximately the same
  • D. CO-Hb does not exist

Explanation

The bond between carbon monoxide and haemoglobin (carboxyhaemoglobin) is extremely stable, approximately 200-250 times more stable than the bond between oxygen and haemoglobin. This high stability is the reason for the toxicity of carbon monoxide.

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Proteins are classified by shape, composition and structure, from primary amino acid sequence to secondary, tertiary and quaternary organisation, and their biological roles are linked to this structure. Enzymes are examined as protein biocatalysts, including active sites, substrate specificity, activation energy, cofactors and factors affecting activity.

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