The administration of penicillin G along with probenicid result in_____________?
Correct answer: D. Decreased renal excretion of penciling G
- A. Increased excretion of probenacid in the feaces and perspiration
- B. Increased excretion of probenacid in urine
- C. Increased metabolis of penciling G
- D. Decreased renal excretion of penciling G
Explanation
Probenecid inhibits renal tubular secretion of penicillin G, reducing its renal excretion and prolonging its plasma half-life. This interaction is used to maintain higher penicillin concentrations.
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