Moderate

The activity of the following enzyme is affected by biotin deficiency____________?

Correct answer: D. Carboxylase

  • A. Transketolase
  • B. Dehydrogenase
  • C. Oxidase
  • D. Carboxylase

Explanation

Biotin carries carbon dioxide in carboxylation reactions, so enzymes such as pyruvate carboxylase and acetyl-CoA carboxylase lose activity during biotin deficiency. Transketolase instead depends on thiamine pyrophosphate.

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