Tetracyclines act by__________________?
Correct answer: A. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex
- A. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex
- B. Inhibiting peptidyl transferase
- C. Inactivating elongation factors
- D. Causing misreading of mRNA
Explanation
Tetracyclines bind the bacterial 30S ribosomal subunit and block attachment of aminoacyl-tRNA to the acceptor site. Peptidyl-transferase inhibition is characteristic of some 50S inhibitors, not tetracyclines.
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