_ suggested that each enzyme had a particular shape into which the substrate fit exactly.
Correct answer: C. Emil Fischer
- A. Koshland
- B. Robert Whittaker
- C. Emil Fischer
- D. Michael Menten
Explanation
Emil Fischer proposed the "lock and key" model, which suggests that enzymes and substrates have specific complementary shapes that allow them to fit together like a lock and key. This model implies that the enzyme's active site is already in the appropriate shape for the substrate to bind, without requiring significant conformational changes.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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