Smallpox is a _.

Explanation

The smallpox virus (Variola virus) has a double-stranded DNA (dsDNA) genome, which is large and linear, encoding all the proteins needed for its replication and assembly. Unlike most DNA viruses, it replicates entirely in the cytoplasm of the host cell, carrying its own enzymes for transcription and DNA replication. Its genome is surrounded by a complex protein capsid and a lipid envelope, which helps the virus enter host cells and evade immune defences. This DNA genome allows the virus to produce all the components necessary for infection and spread, making it a highly efficient and pathogenic virus.