Sickle cell hemoglobin has reduced ability to:
Correct answer: B. Carry O2
- A. Carry CO2
- B. Carry O2
- C. Release O2
- D. Release CO2
Explanation
Sickle cell hemoglobin, due to its modified β-globin chains, forms an abnormal structure that reduces its ability to carry oxygen (O2) efficiently. This structural alteration causes the hemoglobin to polymerize under low oxygen conditions, leading to sickle-shaped red blood cells. These cells are less effective at transporting oxygen throughout the body. Options A, C, and D are incorrect because they focus on carbon dioxide transport or oxygen release, which are not primarily affected in sickle cell disease.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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