Sickle cell anemia is an example of_________________?
Correct answer: D. Point mutation
- A. Chromosomal aberration
- B. Insertion of gene
- C. Deletion of gene
- D. Point mutation
Explanation
Sickle-cell anaemia results from a single nucleotide substitution in the beta-globin gene, which changes one amino acid in haemoglobin, so it is a point mutation. The likely alternative is chromosomal aberration, but that involves a large change in chromosome structure or number rather than a change at one gene position.
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