Select the correct statement with respect to disorders of muscles in humans.
Correct answer: A. Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
- A. Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
- B. Accumulation of urea and creatine in the joints causes their inflammation.
- C. An overdose of vitamin D causes osteoporosis.
- D. Rapid contractions of skeletal muscles cause muscle dystrophy.
Explanation
Myasthenia gravis is an autoimmune disorder in which autoantibodies bind to cholinergic receptors on muscle cells and impairs the ability of the neurotransmitter acetylcholine to induce muscular contraction. This leads to fatigue, weakening and paralysis of skeletal muscles of mouth and throat which may prevent normal swallowing.B) Gouty arthritis is caused either due to excessive formation of uric acid or inability to excrete it. It gets deposited in synovial joints and causes inflammation.C) Osteoporosis is a disease in which bone loses minerals and fibres from its matrix. Major causative factors of osteoporosis are imbalances of hormones like calcitonin of thyroid, parathormone of parathyroids, sex hormones and deficiencies of calcium and vitamin D.D) Muscular dystrophy is inborn abnormality of muscles associated with dysfunction and ultimately with deterioration.
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About Support and Movement
Support and movement covers the axial and appendicular skeleton, bone structure, joints and the arrangement of skeletal muscles. Muscle contraction is explained through actin, myosin, sliding filaments, calcium ions and ATP, while arthritis is distinguished as a disorder of joints rather than a normal part of movement.
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