Rate limiting step in cholesterol synthesis is_______________?
Correct answer: A. HMG CoA reductase
- A. HMG CoA reductase
- B. HMG CoA lyase
- C. HMG CoA synthetase
- D. Mevalonate synthetase
Explanation
HMG-CoA reductase catalyses the conversion of HMG-CoA to mevalonate and is the rate-limiting, highly regulated step of cholesterol synthesis. HMG-CoA synthetase and lyase have different roles in HMG-CoA metabolism.
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