Pyruvic acid, before entering the Krebs cycle, is changed to
Correct answer: D. Acetyl-CoA
- A. Succinic acid
- B. Citric acid
- C. Malic acid
- D. Acetyl-CoA
Explanation
Acetyl-CoA is the correct option because pyruvic acid is converted into acetyl-CoA before entering the Krebs cycle. This conversion occurs in the mitochondria through a process called oxidative decarboxylation, where one molecule of carbon dioxide is released and NAD⁺ is reduced to NADH. The resulting acetyl-CoA then combines with oxaloacetic acid to form citric acid, marking the start of the Krebs cycle. Succinic acid, citric acid, and malic acid are all intermediates formed later within the cycle and are not directly produced from pyruvic acid. Therefore, acetyl-CoA is the only compound that serves as the direct link between glycolysis and the Krebs cycle.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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In the conversion of pyruvic acid to acetyl coenzyme-A, pyruvic acid gets:
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