People who have migrated from the planes to a higher altitude area about six months back:
Correct answer: A. Have more RBCs and their hemoglobin has a lower binding affinity to O2 .
- A. Have more RBCs and their hemoglobin has a lower binding affinity to O2 .
- B. Are not physically fit to play games like football.
- C. Suffer from altitude sickness with symptoms like nausea, fatigue, etc.
- D. Have the usual RBC count but their haemoglobin has a very high binding affinity to O 2.
Explanation
After about six months at high altitude the body acclimatises: it produces more red blood cells (polycythaemia) and raises 2,3-BPG, which shifts the oxygen-haemoglobin curve to the right, lowering haemoglobin's O₂ binding affinity so more O₂ is released to the tissues.
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The human respiratory system includes the air passages, lungs, alveoli and breathing muscles, while gaseous exchange explains how oxygen enters blood and carbon dioxide leaves it by diffusion. The effects of smoking include damage to cilia and alveoli, reduced gas exchange, chronic bronchitis, emphysema and increased risk of lung cancer.
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