Out of the following hypersensitivity reactions, in which type a single dose of the antigen can act as both the sensitizing and shocking dose_______________?
Correct answer: C. Serum sickness
- A. Anaphylaxis
- B. Arthus reaction
- C. Serum sickness
- D. Contact dermatitis
Explanation
In serum sickness, one large antigen dose can provide the initial sensitisation and later produce immune-complex disease as antibody develops. Anaphylaxis and the Arthus reaction classically require a prior sensitising exposure followed by a challenging exposure.
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