Osteoporosis, an age related disease of skeletal system, may occur due to:
Correct answer: C. Decreased level of estrogen
- A. Immune disorder affecting neuromuscular junction leading to fatigue
- B. High concentration of Ca2+ and Na+
- C. Decreased level of estrogen
- D. Accumulation of uric acid leading to inflammation of joints
Explanation
Osteoporosis is a reduction in bone mineral density, resulting in bones that are brittle and liable to fracture. Infection, injury, and synovitis can cause localized osteoporosis of adjacent bone. Generalized osteoporosis is common in the elderly and in women after menopause. After menopause, the estrogen levels in blood plasma are much reduced. Estrogen helps to regulate bone cells called osteoclasts which are responsible for building new bone. When estrogen levels drop fewer osteoclasts are produced resulting in osteoporosis. A. Osteoporosis is not an immune disorder. B. High concentrations of Ca and Na donot lead to osteoporosis. D. This happens in Gouty arthritis.
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About Support and Movement
Support and movement covers the axial and appendicular skeleton, bone structure, joints and the arrangement of skeletal muscles. Muscle contraction is explained through actin, myosin, sliding filaments, calcium ions and ATP, while arthritis is distinguished as a disorder of joints rather than a normal part of movement.
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