One molecule of FADH2 is produced in Krebs's cycle during conversion of:
Correct answer: B. Succinate to Fumarate
- A. Fumarate to Malate
- B. Succinate to Fumarate
- C. Malate to Oxaloacetate
- D. α-Ketoglutarate to Succinate
Explanation
One molecule of FADH2 is produced in the Krebs cycle during the conversion of succinate to fumarate. The specific reaction involves the enzyme succinate dehydrogenase, which catalyzes the oxidation of succinate. The chemical reaction can be represented as follows: Succinate + FAD (flavin adenine dinucleotide) → Fumarate + FADH2 In this reaction, succinate is oxidized to fumarate, and FAD is reduced to form FADH2. The electrons removed from succinate are transferred to FAD, and the resulting FADH2 carries these electrons to the electron transport chain, where they contribute to the generation of ATP during oxidative phosphorylation in later stages of cellular respiration.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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