Nucleophilic addition reactions of carbonyl compounds can be catalyzed by_?
Correct answer: D. Both acid and base
- A. Acid
- B. Base
- C. Water
- D. Both acid and base
Explanation
Nucleophilic addition reactions of carbonyl compounds can be catalyzed by bases where a strong nucleophilic reagent attacks the electrophilic carbon such as addition of hydrogen cyanide, addition of grignard's reagent, addition of sodium bisulphate etc. However, nucleophilic additions are also catalyzed by acids, which increases the electrophilic character of carbonyl carbon so that the weak electrophile can attack the electrophilic carbon easily. Examples of such reactions are polymerization of aldehydes, addition of alcohols with aldehydes etc.
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About Aldehydes and Ketones
Aldehydes and ketones contain the polar carbonyl group, but aldehydes are generally more readily oxidised and more reactive than ketones. Coverage includes preparation by oxidation or reduction routes, nucleophilic addition of reagents such as hydrogen cyanide and bisulfite, and tests that distinguish aldehydes from ketones.
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