Moderate
NK cells are effective against viral infected cells only if the cell with infection___________?
Correct answer: B. Unable to express MHC class I proteins
- A. Exprss MHC class I proteins
- B. Unable to express MHC class I proteins
- C. Express MHC class II proteins
- D. Unable to express MHC class II proteins
Explanation
NK cells preferentially attack infected or tumour cells that have lost or markedly reduced MHC class I expression, removing the normal inhibitory signal. This is called “missing-self” recognition.
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