Name the inhibitors which can be neutralized by adding more substrate:
Correct answer: A. Competitive Inhibitors
- A. Competitive Inhibitors
- B. Permanent inhibitors
- C. Non-competitive inhibitors
- D. Irreversible inhibitors
Explanation
A competitive inhibitor is a substance similar in structure to an enzyme's substrate that binds to the active site and inhibits a reaction.It blocks the active site of an enzyme and by increasing the concentration of substrate,the effect of a competitive inhibitor can be neutralized.For Example:Malonic acid is a competitive inhibitor of enzyme succinic dehydrogenase.On the other hand, the irreversible inhibitor doesn't compete with the natural active site for substrate but it combines with the site other than the active site.For Example:Cyanide action on cytochrome oxidase.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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