Most disease symptoms appear during.

Explanation

After the lag phase, bacterial cells enter the exponential or log phase. This is the time when the cells are dividing by binary fission and doubling in numbers after each generation time. Metabolic activity is high as DNA, RNA, cell wall components, and other substances necessary for growth are generated for division. In humans, the disease symptoms develop during the log phase because the bacterial production attains such a high level which damages the tissues.