Mechanism of action of beta-lactam antibiotics would be______________?
Correct answer: B. Inhibition of cell wall peptidoglycan synthesis by competitive inhibition of transpetidases
- A. Inhibition of bacterial protein synthesis by binding to subunit of bacterial ribosomes
- B. Inhibition of cell wall peptidoglycan synthesis by competitive inhibition of transpetidases
- C. Reduced drug causes strand breaks in DNA
- D. Inhibition of DNA synthesis by inhibiting DNA-Dependent RNA polymerase
Explanation
Beta-lactams bind penicillin-binding proteins and competitively inhibit transpeptidases, preventing cross-linking of peptidoglycan in the bacterial cell wall. Their primary action is therefore not on ribosomes or DNA.
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