Moderate

Ligant for peroxisome proliferation activating receptor (PPAR) receptors, a group of nuclear hormone receptors that are involved in the regulation of genes related to glucose and lipid metabolism is_____________?

Correct answer: D. Rosiglitgazone

  • A. Repaglinide
  • B. Voglibose
  • C. Exanatide
  • D. Rosiglitgazone

Explanation

Rosiglitazone activates PPAR-gamma, a nuclear receptor that regulates genes involved in insulin sensitivity and glucose and lipid metabolism. The other drugs act through different pathways and are not PPAR ligands.

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