Levamisole mainly affects nematodes by causing:
Correct answer: C. Spastic paralysis through nicotinic receptors
- A. Inhibition of folate synthesis
- B. Disruption of tegument through bile salts
- C. Spastic paralysis through nicotinic receptors
- D. Blockage of parasite mitochondrial respiration
Explanation
Levamisole acts as a nicotinic acetylcholine receptor agonist at the nematode neuromuscular junction, producing sustained contraction and spastic paralysis. Folate inhibition and microtubule disruption are mechanisms associated with other drug groups.
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Covers protozoa, helminths and arthropods that infect domestic animals, including their morphology, life cycles, hosts, transmission and clinical effects. Questions connect parasite identification with diagnosis, prevention and treatment, and distinguish endoparasites from ectoparasites and definitive hosts from intermediate hosts.
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