Ivermectin acts against many parasitic nematodes mainly by affecting which target?
Correct answer: B. Glutamate-gated chloride channels
- A. Acetylcholinesterase
- B. Glutamate-gated chloride channels
- C. Folate synthesis
- D. Fungal ergosterol synthesis
Explanation
Ivermectin increases chloride ion conductance through glutamate-gated chloride channels in parasite nerve and muscle cells, causing paralysis. Acetylcholinesterase inhibition is associated with organophosphate compounds, not ivermectin.
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About Veterinary Parasitology
Covers protozoa, helminths and arthropods that infect domestic animals, including their morphology, life cycles, hosts, transmission and clinical effects. Questions connect parasite identification with diagnosis, prevention and treatment, and distinguish endoparasites from ectoparasites and definitive hosts from intermediate hosts.
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