In uncompetitive inhibition, the inhibitor binds with ----------

Explanation

Option C is correct since uncompetitive inhibition occurs when an inhibitor binds to an allosteric site of an enzyme, but only when the substrate is already bound to the active site. In other words, an uncompetitive inhibitor can only bind to the enzyme-substrate complexOption A is incorrect because uncompetitive inhibitors do not bind to free enzymes.Option B is incorrect because inhibitors do not bind to the substrate but to the enzymes. The substrate is thereby prevented from binding to the enzyme.Option D is incorrect because uncompetitive inhibitors bind to the enzyme-substrate complex only.