Moderate

In the Krebs cycle, substrate-level phosphorylation accompanies the formation of:

Correct answer: C. Succinate

  • A. Citrate
  • B. Alpha-ketoglutarate
  • C. Succinate
  • D. Fumarate
  • E. Oxaloacetate

Explanation

In the Krebs cycle, also known as the citric acid cycle, the formation of succinate involves a series of chemical reactions, and substrate-level phosphorylation does not take place during the conversion of succinyl-CoA to succinate. The specific step where substrate-level phosphorylation occurs in the Krebs cycle is during the conversion of succinyl-CoA to succinate. In this step, the enzyme succinyl-CoA synthetase is involved, and it catalyzes the transfer of a phosphate group from succinyl-CoA to ADP, producing ATP and succinate. The overall reaction is as follows: Succinyl-CoA + ADP + Pi (inorganic phosphate) → Succinate + ATP

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About Bioenergetics

Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.

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