In the earliest stages of carious lesion. There is loss of______________?

Correct answer: A. Interprismatic substance

  • A. Interprismatic substance
  • B. Enamel cuticle
  • C. Organic matrix
  • D. Enamel lamellae

Explanation

The earliest enamel caries preferentially removes mineral from the interprismatic substance, producing microscopic porosity before more extensive matrix changes occur. This is why loss of interprismatic substance is the best answer.

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