In HIV, gp 120, envelope glycoproteins bind specifically to______________?
Correct answer: B. CD4 T-cells
- A. CD8 T-cells
- B. CD4 T-cells
- C. B - cells
- D. NK - cells
Explanation
HIV gp120 attaches first to the CD4 receptor on helper T lymphocytes, followed by interaction with a chemokine coreceptor such as CCR5 or CXCR4. CD8 cells, B cells and NK cells do not provide the primary receptor for gp120.
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