In HIV, gp 120, envelope glycoproteins bind specifically to______________?

Correct answer: B. CD4 T-cells

  • A. CD8 T-cells
  • B. CD4 T-cells
  • C. B - cells
  • D. NK - cells

Explanation

HIV gp120 attaches first to the CD4 receptor on helper T lymphocytes, followed by interaction with a chemokine coreceptor such as CCR5 or CXCR4. CD8 cells, B cells and NK cells do not provide the primary receptor for gp120.

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