In acute inflammation, immediate transient permeability in cells is increased by__________?
Correct answer: B. Endothelial Gaps by histamine
- A. Direct injury & necrosis
- B. Endothelial Gaps by histamine
- C. Leucocyte mediated endothelial injury
- D. Increased tissue oncotic pressure
Explanation
The immediate transient response is mainly caused by histamine-induced contraction of endothelial cells in postcapillary venules, producing interendothelial gaps. Direct necrosis causes a more severe and sustained response rather than the classic immediate transient reaction.
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