IF a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because_______________?
Correct answer: D. Penicillin is only effective against growing cells
- A. Penicillin is inactivated by erythromycin
- B. Erythromycin exerts its effects extracellularly
- C. Erythromycin enhances the B-lactamases activity
- D. Penicillin is only effective against growing cells
Explanation
Penicillins kill actively growing bacteria, whereas erythromycin is bacteriostatic and inhibits their growth, so the two effects can be antagonistic when used together. Erythromycin does not inactivate penicillin or increase beta-lactamase activity.
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