Hemophilia is a:
Correct answer: B. Both of these
- A. None of these
- B. Both of these
- C. Mendelian trait
- D. Chromosomal disorder
Explanation
Hemophilia is a Mendelian trait that is also an X chromosome-linked recessive disorder. X-linked recessive trait means a trait that is only expressed on the X chromosome. Because the traits or mutations are only present on the X chromosome, males only require 1 defective X chromosome to acquire the disease whereas females require 2 defective X chromosomes. Therefore, these traits are much more common in men as compared to women. Examples of X-linked recessive traits include Hemophilia A and B, color blindness, etc.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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