Hemoglobin is the major buffer in blood, bicarbonate ions diffuse out of erythrocyte into plasma in exchange of_______________?
Correct answer: B. Chloride ion
- A. Potassium
- B. Chloride ion
- C. Carbonic acid
- D. Phosphate
Explanation
In systemic tissues, bicarbonate leaves the erythrocyte and chloride enters it through the anion exchanger, a process called the chloride shift. This maintains electrical neutrality while carbon dioxide is transported mainly as plasma bicarbonate.
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