Grignard reagent is produced by the reaction of Alkyl halides with _?
Correct answer: B. Mg in dry ether
- A. Ca in anhydrous ether
- B. Mg in dry ether
- C. Mg in hydrous ether
- D. Ca in dry ether
Explanation
Option A: This option is incorrect. Grignard reagents are not typically prepared using calcium (Ca) metal. The commonly used metal for the preparation of Grignard reagents is magnesium (Mg). Option B: Mg in dry ether: This option is correct. Grignard reagents are most commonly prepared by reacting alkyl halides (such as alkyl iodides, bromides, or chlorides) with magnesium metal (Mg) in the presence of a dry ether solvent, typically diethyl ether or tetrahydrofuran (THF). The reaction forms a Grignard reagent, which is an organo magnesium compound. Option C: This option is incorrect. Grignard reagents are typically prepared in dry ether solvents, not hydrous (water-containing) ethers. The presence of water can interfere with the formation and stability of Grignard reagents. Option D: This option is incorrect. While calcium (Ca) can react with certain organic compounds, it is not commonly used for the preparation of Grignard reagents. Magnesium (Mg) is the metal of choice for generating Grignard reagents due to its higher reactivity and greater compatibility with organic halides.
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About Alkyl Halides
Alkyl halides are named and related to their carbon-halogen structure, polarity and reactivity. The key reactions are nucleophilic substitution by SN1 and SN2 mechanisms and elimination by E1 and E2 mechanisms, including how substrate structure, nucleophile, base, solvent and temperature influence substitution versus elimination.
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