From one pyruvate passing through Krebs cycle, how many NADH are formed?

Correct answer: C. 3

  • A. 1
  • B. 2
  • C. 3
  • D. 4

Explanation

In the Krebs cycle, also known as the citric acid cycle, one molecule of acetyl-CoA enters the cycle, which is derived from one molecule of pyruvate. During the cycle, a series of enzymatic reactions occur, resulting in the complete oxidation of the acetyl group to carbon dioxide. This process simultaneously produces high-energy molecules: three NADH, one FADH2, and one ATP (or GTP). Therefore, starting with one pyruvate molecule, the Krebs cycle specifically yields three NADH molecules per cycle.Options suggesting one, two, or four NADH molecules are incorrect because they do not accurately reflect the output of the Krebs cycle from one pyruvate-derived acetyl-CoA.

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Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.

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