Feedback inhibition in most metabolic pathways involves which type of enzymes?
Correct answer: D. Allosteric enzymes
- A. Holoenzymes
- B. Coenzymes
- C. Apoenzymes
- D. Allosteric enzymes
Explanation
Allosteric enzymes are enzymes that change their conformational ensemble upon binding of an effector which results in an apparent change in binding affinity at a different ligand binding site. In feedback inhibition, the product of the enzymatic reaction gets attached to the allosteric site of an enzyme having an allosteric site and stops the reaction from happening. Feedback inhibition in most metabolic pathways typically involves the inhibition of the first enzyme in the pathway, often by the final product of that pathway. This type of regulation helps maintain homeostasis and prevents the overproduction of certain metabolites.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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