FADH2 is produced during:
Correct answer: C. Krebs cycle
- A. Glycolysis
- B. The oxidation of pyruvates
- C. Krebs cycle
- D. All of these
Explanation
FADH2 is indeed produced during the Krebs cycle, which is also known as the citric acid cycle or TCA (tricarboxylic acid cycle). The Krebs cycle is the second stage of cellular respiration and takes place in the mitochondrial matrix. It is a central metabolic pathway that involves the oxidation of acetyl-CoA (derived from pyruvate) to generate ATP, NADH, FADH2, and carbon dioxide.During the Krebs cycle, the reduced form of FAD (FADH2) is produced through the following reaction:Fumarate + FAD → Malate + FADH2In this reaction, FAD accepts two hydrogen atoms (two electrons and two protons) from fumarate, becoming reduced to FADH2. The reaction is catalyzed by the enzyme succinate dehydrogenase.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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