Asked in PMC Practice Test 17 (2021) 2021

Edward Jenner began inoculating humans with material from lesions caused by which disease?

Correct answer: D. Cowpox

  • A. Chickenpox
  • B. Smallpox
  • C. Avian pox
  • D. Cowpox

Explanation

Edward Jenner inoculated humans with cowpox pus. The basis for vaccination began in 1796 when the English doctor Edward Jenner noticed that milkmaids who had gotten cowpox were protected from smallpox. Jenner also knew about variolation and guessed that exposure to cowpox could be used to protect against smallpox. On 14 May 1796, Jenner tested his hypothesis by inoculating James Phipps, an eight-year-old boy who was the son of Jenner's gardener. He scraped pus from cowpox blisters on the hands of Sarah Nelmes, a milkmaid who had caught cowpox from a cow. So, option D is correct.

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