Disruption of the protein structure by heating, changes in pH, and by chemicals is called _.

Explanation

Option A: Coagulation is defined as the change in the structure of protein (from a liquid form to solid or a thicker liquid) brought about by heat, mechanical action or acids.Option B: The water of hydration is essential to the structure of protein crystals; when they are completely dehydrated, the crystalline structure disintegrates. In some proteins this process is accompanied by denaturation and loss of the biological functionOption C: The secondary and tertiary structure of a protein can be disrupted by heating, by pH changes, by high concentrations of substances such as urea or by reducing agents that break the disulphide bonds. The process is calleddenaturation, and it destroys the protein's biological activity.