Complement binding immunoglobin via the classical pathway is_______________?
Correct answer: A. IgG & igM
- A. IgG & igM
- B. IgG & IgA
- C. IgG & IgD
- D. IgD & IgE
Explanation
The classical complement pathway is activated when antigen-bound IgM or IgG exposes Fc regions that bind C1. IgA, IgD and IgE do not normally activate complement through this pathway.
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