Citrate is a useful anticoagulant because of its ability to_____________?
Correct answer: C. Chelate calcium
- A. Buffer basic groups of coagulation factors
- B. Bind factor XII
- C. Chelate calcium
- D. Bind vitamin K
Explanation
Citrate prevents coagulation by binding ionized calcium, which is required at several stages of the coagulation cascade. This reversible calcium chelation is why citrated blood can be used for laboratory testing.
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