Bleeding time is prolonged in a person who_______________?
Correct answer: D. Takes large quantities of aspirin
- A. Has liver disease
- B. Takes coumarin derivatives
- C. Lacks factor VIII
- D. Takes large quantities of aspirin
Explanation
Large doses of aspirin impair platelet cyclooxygenase and thromboxane A2 formation, reducing platelet aggregation and prolonging bleeding time. Coumarin and factor VIII deficiency prolong clotting times, especially PT or PTT, rather than primarily bleeding time.
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