Moderate

Biotin is required for the activity of_____________?

Correct answer: A. Pyruvate carboxylase

  • A. Pyruvate carboxylase
  • B. Lactate dehydrogenase
  • C. Succinate thiokinase
  • D. Phosphohexose isomerase

Explanation

Biotin is the covalently bound cofactor for carboxylases and carries activated carbon dioxide during carboxylation. Pyruvate carboxylase therefore requires biotin, unlike the other listed enzymes.

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